TruEquine™: The Science Behind a More Resilient Horse

by Dr. Chris Mortensen and Dr. Tiffany Hall

Most gut supplements promise a lot.

• Better digestion.
• Stronger immunity.
• Improved performance.

But very few are backed by real equine research.

TruEquine™ is different.

It’s a postbiotic (P-O-S-T) that delivers active compounds that support the gut.

Postbiotics differ sharply from living bacteria, or what nutritionists call “probiotics” (P-R-O), which equine research shows often do not survive manufacturing, storage, or even digestion. 

Research in horses show that TruEquine™ postbiotics work faster, more consistently, and helps horses thrive under real-world conditions. And it's why we chose to include TruEquine™ in DigestiveHP.

Here is what the research says about TruEquine™ postbiotics:

Stronger Gut Stability Even Under Stress

Travel, competition, and routine changes all disrupt the hindgut.

In research trials, horses receiving TruEquine™ postbiotic maintained a more stable microbiome after transport stress. Beneficial bacteria were preserved, while gut disruption was reduced.

• Translation: when under pressure, postbiotics can help stabilize the hindgut microbiome. 

Study reference:
Ganda, E. et al. (2023). Saccharomyces cerevisiae fermentation product improves robustness of equine gut microbiome upon stress. Frontiers in Veterinary Science, 10, 1134092.

Get More from Every Mouthful of Feed

Most horses aren’t limited by how much they eat. They’re limited by the quantity and quality of the nutrients they can extract from their forage.

TruEquine™ postbiotic demonstrates improved fibre digestion and nutrient utilisation, especially when forage quality is lower. Horses on TruEquine™ have increased nutrient production and weight gain compared to horses not on post-biotics.    

Translation: more usable nutrition when it matters most.

This is where TruEquine™ postbiotics makes a real difference for:

• Hard keepers
• Older horses
• Horses on average or lower-quality hay

Study reference:
Morgan, L.M. et al. (2007). Effect of yeast culture supplementation on digestibility of varying forage quality in mature horses. Journal of Equine Veterinary Science 27:260-65. 

Faster Recovery. Better Performance.

Exercise creates stress and inflammation, especially in performance horses.

In studies, horses supplemented with TruEquine™ postbiotic showed:

• Faster return of cortisol to baseline
• Reduced inflammatory markers post-exercise
• Translation: Faster recovery, more consistent performance. 
• Study reference:

Valigura, H. C. et al. (2021). Dietary supplementation of a Saccharomyces cerevisiae fermentation product attenuates exercise-induced stress markers in young horses. Journal of Animal Science, 99(8).

Supports the All-Important Immune System

Most of the immune system is linked to the gut.

TruEquine™ postbiotic has been shown to:

• Improve immune cell function 
• Support response to stress challenges
• Reduce inflammation signals 

Translation: a healthier gut directly supports a stronger, more resilient horse.

Study reference:
Tench, M., et al.  Dietary Saccharomyces cerevisiae fermentate affects mucosal immunity in young stress-challenged horses in training.  Journal of Equine Veterinary Science 100 (2021): 103503.

Supports a Healthier Inflammatory Response - Even in Joints

Inflammation doesn’t just affect the gut, but it impacts joints too.

In a controlled study where joint inflammation was triggered, horses receiving TruEquine™ showed:

• Lower inflammatory markers in the joint
• Improved balance between cartilage breakdown and repair
• Translation: helps the body regulate inflammation more effectively, even at the joint level.

Study reference:
Martinez, R. E. et al. (2021). Responses to an intra-articular lipopolysaccharide challenge following dietary supplementation of Saccharomyces cerevisiae fermentation product in young horses. Journal of Animal Science, 99(10).

More Energy-From the Hindgut Where It Matters

The horse runs on fibre fermentation by the cecal and large colon microbiomes.

TruEquine™ postbiotic increases production of:

• Acetate 
• Propionate 
• Butyrate 

These are the primary energy sources produced in the hindgut.

Translation: better fermentation = more usable energy, without adding starch.

Study reference:
Morgan, L.M. et al. (2007). Effect of yeast culture supplementation on digestibility of varying forage quality in mature horses. Journal of Equine Veterinary Science 27:260-65.

Why TruEquine Works Differently

Most products try to add living bacteria into a system that’s already under pressure.

TruEquine delivers what the gut actually needs:

• Postbiotic compounds 
• Fermentation metabolites 
• Immediate support to the hindgut 
• No guesswork. No reliance on survival through the stomach.

Just functional support where it matters most.

Where TruEquine ™ Postbiotic Fits

TruEquine™ postbiotic isn’t a “band-aid.” TruEquine™ isn’t designed to mask a problem but to improve gastrointestinal functionality in our horses and support them through the many stressors horses experience on a daily basis. 

• It’s a foundational tool for:
• Performance horses under stress 
• Horses with inconsistent manure 
• Horses on variable forage 
• Older horses needing extra support 

The Bottom Line

When the hindgut is stable, everything improves:

• Digestion 
• Energy 
• Immunity 
• Recovery 

That’s what TruEquine™ postbiotic delivers. It's backed by research, and included in DigestiveHP.